Cervical Cancer Prevention: Pap Tests, HPV Testing, and Vaccination

Woman holding teal awareness ribbon

Cervical cancer is one of the most preventable cancers. Regular screening can find cell changes before they become cancer, and HPV vaccination can help prevent the infections that cause most cervical cancers. Together, these tools give women powerful protection at different stages of life.

Most cervical cancers are caused by long-lasting infection with high-risk types of human papillomavirus, or HPV. HPV is very common, and in many cases, the body clears the infection on its own. When a high-risk HPV infection does not go away, it can lead to changes in cervical cells over time. If those changes are not found and treated, they may eventually develop into cervical cancer.

Prevention Starts with Understanding HPV

HPV is a group of viruses spread through intimate skin-to-skin contact. Some types of HPV are considered low-risk and can cause genital warts. Other types are high-risk because they are linked to cancer, including cervical, vaginal, vulvar, anal, penile, and some throat cancers. The National Cancer Institute notes that HPV types 16 and 18 are responsible for about 70% of cervical cancers, while other high-risk HPV types also contribute to cervical cancer risk.

Because HPV often has no symptoms, someone can have it without knowing. That is why routine screening matters. Cervical cancer prevention is not just about checking for cancer — it is about finding HPV or abnormal cervical cell changes early enough to prevent cancer from developing.

Pap Tests and HPV Tests: What’s the Difference?

The two main screening tools for cervical cancer are the Pap test and the HPV test. A Pap test, sometimes called a Pap smear, looks for abnormal or precancerous cell changes on the cervix. An HPV test looks for the virus that can cause those cell changes. Both tests can help prevent cervical cancer or find it early.

For women ages 21 to 29, cervical cancer screening is generally done with a Pap test every three years if results are normal. HPV testing is not typically recommended as routine co-testing for women younger than 30. For women ages 30 to 65, current federal women’s preventive services guidance recommends primary high-risk HPV testing every five years as the preferred option, or Pap and HPV co-testing every five years. If HPV testing is unavailable, Pap testing alone every 3 years remains an option.

A common misconception is that women need a Pap test every year. For most women at average risk, annual Pap testing is not recommended. However, this does not mean skipping annual wellness visits. A yearly checkup is still important for reviewing overall health, vaccines, menstrual or menopause symptoms, sexual health, contraception, family history, and other preventive care needs.

What Happens if a Result Is Abnormal?

An abnormal Pap or HPV test result does not usually mean cancer. It often means that HPV or cervical cell changes were found and that more follow-up is needed. Depending on the result, a provider may recommend repeat testing, HPV genotyping, a closer examination of the cervix called colposcopy, or a biopsy. The CDC emphasizes that when abnormal or precancerous cells are found, appropriate follow-up and treatment can prevent cervical cancer from developing in most cases.

The most important step after an abnormal result is to avoid delaying follow-up. Cervical cancer usually develops slowly, and timely evaluation gives providers the best opportunity to monitor or treat cell changes before they become serious.

HPV Vaccination: Cancer Prevention Before Exposure

HPV vaccination is another major tool in cervical cancer prevention. The CDC recommends routine HPV vaccination at ages 11 or 12, though vaccination can begin as early as age 9. Catch-up vaccination is recommended through age 26 for those who were not adequately vaccinated earlier.

Some adults aged 27 through 45 may also choose to get the HPV vaccine after talking with a health care provider. The vaccine offers less benefit for many adults in this age range because they may have already been exposed to HPV, but it can still be helpful for some people, depending on their risk for new HPV infection.

The HPV vaccine prevents new HPV infections, but it does not treat existing HPV infections or cervical cell changes. That is why the vaccine works best when given before exposure to HPV, and why women who have been vaccinated still need cervical cancer screening according to their age and health history.

HPV vaccination is not only for girls. Vaccinating boys and young men also helps prevent HPV-related cancers, including anal, penile, and some throat cancers, and helps reduce the spread of HPV overall.

Screening After Age 65

Many women can stop routine cervical cancer screening after age 65 if they have had adequate normal screening results and do not have a history of cervical precancer or cervical cancer. The CDC notes that a provider may recommend stopping screening after age 65 if a woman has had three normal Pap tests or two normal HPV tests in the past 10 years, has no history of cervical precancer, or has had the cervix removed as part of a total hysterectomy for non-cancerous reasons.

Women with a history of cervical cancer, high-grade precancerous changes, HIV, a weakened immune system, or certain other risk factors may need a different screening schedule. Anyone unsure about their screening history or hysterectomy status should ask a health care provider for recommendations.

A Newer Option: Self-Collected HPV Testing

Screening options are continuing to expand. In 2026, HRSA announced updated women’s preventive services guidelines that include self-collected high-risk HPV testing as an appropriate option for average-risk women ages 30 to 65. This option may help reduce barriers for women who avoid or delay screening because of discomfort, trauma history, transportation challenges, time constraints, or limited access to care.

Self-collection is not a replacement for follow-up care. If a self-collected HPV test is positive, additional testing may be needed to complete the screening process, such as cytology, colposcopy, biopsy, or other evaluation, depending on the result.

Reducing Risk Beyond Screening and Vaccination

Pap tests, HPV testing, and vaccination are the most important prevention tools, but other choices can also support cervical health. Not smoking is important because tobacco use increases cervical cancer risk and can make it harder for the immune system to fight HPV. Condoms can lower the risk of HPV transmission, though they do not eliminate the risk completely because HPV can infect areas not covered by a condom.

Women should also talk with a provider about any personal risk factors that may affect screening recommendations, including HIV, immunosuppressant medications, prior abnormal Pap or HPV results, a history of cervical precancer, or exposure to DES before birth.

The Bottom Line

Cervical cancer prevention is a success story in public health because it gives women multiple ways to lower their risk. HPV vaccination helps prevent the infections that cause most cervical cancers. Pap and HPV testing can find early warning signs before cancer develops. Follow-up care can treat abnormal changes before they become life-threatening.

The best prevention plan is simple: get vaccinated when recommended, follow the cervical cancer screening schedule that is right for your age and health history, and do not delay follow-up if a test result is abnormal. Regular preventive care gives women the strongest chance to stay healthy and catch concerns early.

A Women’s Health Preventive Care Checklist for Every Stage of Life

Smiling woman with yoga ball

Preventive care is one of the most important tools for staying healthy as we age. While some screenings are specific to women—such as mammograms, cervical cancer screenings, and bone density testing—many recommended health checks apply to everyone, including blood pressure, cholesterol, diabetes, colorectal cancer screening, vaccines, and mental health care.

This checklist is a general guide for adults at average risk. Your personal recommendations may be different based on family history, symptoms, pregnancy history, menopause, smoking history, medical conditions, medications, or prior test results. A yearly wellness visit is a good time to review what screenings, vaccines, and lifestyle steps are right for you.

In Your 20s and 30s: Build the Foundation

Preventive health starts well before midlife. During these years, regular checkups help establish baselines for blood pressure, weight, cholesterol, reproductive and mental health, and lifestyle habits.

Women should begin cervical cancer screening at age 21, unless their health care provider recommends otherwise based on their personal medical history. For people ages 21 to 29, the U.S. Preventive Services Task Force recommends a Pap test every 3 years. For ages 30 to 65, screening options include a Pap test every 3 years, a high-risk HPV test every 5 years, or co-testing with both Pap and HPV every 5 years.

Sexual health is also part of preventive care. The CDC recommends that everyone ages 13 to 64 be tested for HIV at least once. Sexually active women younger than 25 should also be tested yearly for chlamydia and gonorrhea. Women 25 and older may need annual testing depending on risk factors such as new or multiple partners.

Vaccines matter in adulthood, too. The CDC recommends HPV vaccination routinely at ages 11–12, catch-up vaccination through age 26, and shared decision-making for some adults ages 27–45 who were not previously vaccinated. Adults should also stay current with recommended vaccines, including flu, COVID-19, Tdap/Td, hepatitis B, MMR, varicella, and others, based on age, health status, pregnancy, travel, work, or other risk factors.

Healthy habits built early pay off later. Aim for regular physical activity, a balanced diet, adequate sleep, tobacco avoidance, limited alcohol, sun protection, and routine dental and vision care. Adults should aim for at least 150 minutes of moderate-intensity physical activity each week, plus two days of muscle-strengthening activity.

In Your 40s: Add Cancer and Heart Health Conversations

Your 40s are an important time to take a closer look at cancer prevention, heart health, metabolism, and bone health — especially as perimenopause may begin for some women.

Breast cancer screening generally begins at age 40 for women at average risk. The U.S. Preventive Services Task Force recommends screening mammograms every other year from ages 40 through 74. Women with a strong family history, known genetic risk, prior chest radiation, dense breasts, or previous breast concerns should talk with a health care provider about whether earlier or more frequent screening is appropriate.

Heart health should also be a priority. Blood pressure, cholesterol, blood glucose, body weight, smoking, diet, physical activity, and sleep are all important factors to review during preventive visits. After age 40, clinicians often use risk calculators to estimate the chance of heart disease or stroke.

Diabetes screening becomes especially important in midlife. The U.S. Preventive Services Task Force recommends screening adults ages 35 to 70 who are overweight or obese for prediabetes and type 2 diabetes, with referral to effective preventive interventions when prediabetes is found.

This is also a good decade to discuss menstrual changes, heavy bleeding, hot flashes, sleep disruption, mood changes, urinary symptoms, sexual health, and family history of breast, ovarian, uterine, colorectal, or heart disease.

In Your 50s: Prioritize Colorectal, Breast, Bone, and Menopause Health

At age 45, colorectal cancer screening becomes a routine recommendation for adults at average risk. Screening options may include stool-based tests, colonoscopy, flexible sigmoidoscopy, or CT colonography. Colonoscopy is one of the best-known options, and if results are normal, it is often repeated every 10 years; however, the right test and timing should be decided with a healthcare provider. Adults ages 45 to 75 should be screened for colorectal cancer, while screening for those ages 76 to 85 should be individualized.

Mammograms should continue through this decade, generally every other year for average-risk women ages 40 to 74 under U.S. Preventive Services Task Force guidance. Cervical cancer screening should also generally continue through age 65 for women who still need this screening, depending on their health history and prior results.

Bone health deserves special attention after menopause, when declining estrogen can accelerate bone loss. Calcium and vitamin D are both important for maintaining strong bones. Not getting enough calcium can cause the body to draw calcium from bones over time, weakening them and increasing the risk of osteoporosis. Weight-bearing exercise, strength training, fall prevention, and not smoking also support bone health.

This is also the decade when many women experience menopause. Preventive visits are a good time to talk about hot flashes, sleep, mood, weight changes, vaginal dryness, urinary symptoms, sexual comfort, cardiovascular risk, and bone density risk.

In Your 60s and Beyond: Focus on Strength, Independence, and Early Detection

Women age 65 and older should be screened for osteoporosis with bone density testing, usually with a DXA scan. Postmenopausal women younger than 65 may also need screening if they have risk factors such as low body weight, parental history of hip fracture, smoking, excess alcohol use, or other clinical risks.

Preventive care in this stage should also include fall risk, balance, muscle strength, medications, vision, hearing, dental health, memory concerns, mood, sleep, nutrition, and social connection. For adults 65 and older, regular physical activity should include aerobic exercise, muscle-strengthening activity, and balance activities each week.

Vaccines become increasingly important with age. Depending on age and medical history, adults may need shingles vaccination, pneumococcal vaccination, flu vaccination every year, updated COVID-19 vaccination, RSV vaccination, and other vaccines based on individual risk. The CDC adult immunization schedule is updated regularly, so vaccine needs should be reviewed at least once a year.

Some adults may also qualify for lung cancer screening. The U.S. Preventive Services Task Force recommends annual low-dose CT screening for adults ages 50 to 80 who have a 20-pack-year smoking history and currently smoke or quit within the past 15 years.

Preventive Care for Every Age

Some health checks are important throughout adulthood. Blood pressure should be checked regularly, and high readings should be confirmed outside the clinical setting before treatment begins. Depression screening is also recommended for adults, including pregnant and postpartum women and adults age 65 and older, with follow-up evaluation and care when screening is positive.

At every age, ask your health care provider about:

  • Blood pressure, cholesterol, diabetes risk, and heart health
  • Cervical, breast, colorectal, lung, and skin cancer screening when appropriate
  • Vaccines based on age, pregnancy, health conditions, job, travel, and risk factors
  • Sexual health, HIV/STI testing, and contraception or pregnancy planning when relevant
  • Bone health, especially after menopause
  • Nutrition, including calcium, vitamin D, protein, fiber, and hydration
  • Physical activity, strength training, balance, and fall prevention
  • Tobacco, alcohol, sleep, stress, and mental health
  • Medication review, especially for older adults

Preventive care is not one-size-fits-all. The best checklist is one you review regularly with a trusted health care provider—one that reflects your age, body, family history, lifestyle, and goals for healthy aging.

Breast Cancer Awareness Month 2024: The Importance of Screening and Early Detection

woman receiving mammogram

Breast Cancer Awareness Month 2024: The Importance of Screening and Early Detection

Breast cancer remains one of the most common cancers affecting women in the United States. According to the American Cancer Society (ACS), it is projected that 310,720 new cases of invasive breast cancer will be diagnosed in 2024, and 42,500 women are expected to die from the disease.

While these numbers are concerning, there is good news: early detection plays a critical role in improving survival rates. When breast cancer is detected early, is in the localized stage, and treated promptly, the five-year survival rate is 99%. This underscores the vital importance of regular breast cancer screenings.

Why is Breast Cancer Screening Important?

Breast cancer screening tests, such as mammograms, can detect the disease before symptoms develop, when the cancer is often smaller and has not spread. This early detection makes treatment more effective, less invasive, and can significantly improve outcomes.

For many women, timely screening could be the difference between a manageable condition and a more complicated diagnosis.

Who Should Get Screened?

The ACS recommends that women at average risk of breast cancer start receiving annual mammograms at age 40. Women considered at higher risk—such as those with a family history of breast cancer, certain genetic mutations (like BRCA1 or BRCA2), or other risk factors—may need to begin screenings earlier. It’s important to discuss your personal risk factors with your doctor.

How Often Should I Get Screened?

Most women should have a mammogram every year, according to the ACS guidelines. However, depending on your risk profile, your doctor may recommend a more frequent screening schedule or additional tests such as breast MRIs. Staying consistent with screening is essential for catching any potential issues early.

What Should I Do If I Find a Lump in My Breast?

If you detect a lump or notice any changes in your breasts, it’s crucial to see a healthcare provider promptly. While many breast lumps are not cancerous, only a professional evaluation can determine the cause and recommend the appropriate next steps.

How Can I Support Breast Cancer Awareness Month?

There are many ways you can get involved and help raise awareness:

  • Get screened for breast cancer, and encourage others to do the same.
  • Share information about the importance of screening with friends and family.
  • Donate to breast cancer research or organizations that provide support to patients and survivors.
  • Volunteer your time to local cancer charities or support groups.

By taking these steps, you can contribute to ongoing efforts to reduce breast cancer mortality and support those impacted by the disease.

More Facts About Breast Cancer

January is National Cervical Cancer Awareness Month — What You Need to Know

woman with cervical cancer ribbon

January marks National Cervical Cancer Awareness Month. The American Cancer Society estimated there will have been about 13,960 new cases of invasive cancer diagnosed, and about 4,310 women will have died from cervical cancer in 2023. The 2020 CDC data for Connecticut shows there were 96 cases reported, equaling a cervical cancer rate of 4.8 per 100,000 women.

Anyone with a cervix is at risk for cervical cancer, increasing in people over the age of 30. Certain types of HPV are the main cause of cervical cancer. Screening tests and the HPV vaccine can help reduce the risk of cervical cancer. Click here to see more information about cervical cancer risk.

What is cervical cancer?

Cervical cancer starts in the cells lining the cervix — the lower part of the uterus (womb).

The cervix connects the body of the uterus (the upper part where a fetus grows) to the vagina (birth canal). Cancer starts when cells in the body begin to grow out of control.

The cervix is made of two parts and is covered with two different types of cells.

  • The endocervix is the opening of the cervix that leads into the uterus. It is covered with glandular cells.
  • The exocervix (or ectocervix) is the outer part of the cervix that can be seen by the doctor during a speculum exam. It is covered in squamous cells.

The place where these two cell types meet in the cervix is called the transformation zone. The exact location of the transformation zone changes as you get older and if you give birth. Most cervical cancers begin in the cells in the transformation zone.

Cervical Cancer Symptoms

Cervical cancer may not present with signs or symptoms in its early stages. Advanced cervical can cause bleeding or discharge from the vagina that is not normal for you. The best way to reduce risk is to see your doctor regularly, comply with screening recommendations, and report anything to your doctor that is not normal for you. See the attached documents for more detailed information.

Types of Treatment

If you are diagnosed with cervical cancer, you will be referred to a gynecologic oncologist to develop a treatment plan. Cervical cancer is treated in several ways. It depends on the kind of cervical cancer and how far it has spread. Treatments include surgery, chemotherapy, and radiation therapy.

  • Surgery: Doctors remove cancer tissue in an operation.
  • Chemotherapy: Using special medicines to shrink or kill the cancer. The drugs can be pills you take or medicines given in your veins, or sometimes both.
  • Radiation: Using high-energy rays (similar to X-rays) to kill the cancer.

 Insurance and Income: For those who are concerned they cannot afford care

Screening and treatment are covered under most insurance policies. But what if you, or someone you know, is uninsured or underinsured and cannot afford care? In Connecticut, the DPH has the Connecticut Early Detection & Prevention Program (CEDPP).

The CEDPP is an integrated program that brings breast and cervical cancer screening together with the WISEWOMAN, Colorectal Cancer, and Comprehensive Cancer programs, which helps promote healthy lifestyles for Connecticut Residents in order to decrease breast, cervical, and colorectal cancers, heart disease, hypertension, and other avoidable diseases. If you, or someone you know, needs to receive screening but cannot afford it, please go to the Early Detection and Prevention Program website to determine eligibility.

Cervical Cancer Facts